Studies on the relationship between the infection therapy and the reticuloendothelial system.

position in the mechanism of biological protection against infections, but the marked development of chemotherapy in recent years has produced a tendency to ignore the factors of a living organism in the therapy of infections. On the other hand, wide-spread use of chemotherapeutics has produced problems of resistance and cross-infections. It has become possible to make quantitative examination of the functions of reticuloendothelial system by the development of colloid chemistry and utilization of radioisotopes. It seemed necessary, at this time, to recognize again the role of the reticuloendothelial system in connection with infection, especially on its treatment, and the following examinations were made from such a standpoint. 1) Fundamental examination of the test method for reticuloendothelial functions. 2) Effect of infection on the function of the reticuloendothelial system. 3) Effect of reticuloendothelial functions on infection. 4) Effect of infection therapy on the functions of the reticuloendothelial system.